1t2k_ABCD : 3D-footprint complex

structure name	STRUCTURE OF THE DNA BINDING DOMAINS OF IRF3, ATF-2 AND JUN BOUND TO DNA
reference	Harrison et al. 'Embo 23 4384 2004
source	HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	2pi0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1t2k_A interface=40,76,77,79,80,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvns > 1t2k_B interface=37,39,75,76,78,79,80,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvn > 1t2k_C interface=10,11,14,17,18, mkaerkrmrNRiaAskSRkrkleriarleekvktlkaqnselastanmlreqvaqlkqkvmn > 1t2k_D interface=9,10,12,13,16,17, krrkflerNRaAAsrSRqkrkvwvqslekkaedlsslngqlqsevtllrnevaqlkqllla
interface signature	LRNRSR/HLRNRSAR/NRASR/NRAASR

Estimated binding specificities ?

readout + contact

# IC=16.012 IC/col=0.801 n_of_columns=20

specificity:

A |   0   0   0  96   0  96   8  24  24  15  24  67  96  82  24   5   1  71  96  88
C |   0   0   0   0  96   0   5  24  24   9  24   1   0   3  24   5   3  13   0   4
G |   0   0  96   0   0   0   7  24  24  57  24  23   0   5  24   5  13   7   0   3
T |  96  96   0   0   0   0  76  24  24  15  24   5   0   6  24  81  79   5   0   1

scan!

home
updated Mon Sep 9 14:15:43 2024