1t2k_ABCD : 3D-footprint complex

structure name	STRUCTURE OF THE DNA BINDING DOMAINS OF IRF3, ATF-2 AND JUN BOUND TO DNA
reference	Harrison et al. 'Embo 23 4384 2004
source	HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1t2k_A interface=40,76,77,79,80,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvns > 1t2k_B interface=37,39,75,76,78,79,80,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvn > 1t2k_C interface=10,11,14,17,18, mkaerkrmrNRiaAskSRkrkleriarleekvktlkaqnselastanmlreqvaqlkqkvmn > 1t2k_D interface=9,10,12,13,16,17, krrkflerNRaAAsrSRqkrkvwvqslekkaedlsslngqlqsevtllrnevaqlkqllla
interface signature	LRNRSR/HLRNRSAR/NRASR/NRAASR

Estimated binding specificities ?

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# IC=14.743 IC/col=0.737 n_of_columns=20

specificity:

A |   8   0  10  78  68  24   6   0   8  24  24  24  24  68   0   0   0   0  96  96
C |   8   0   8  12  12  24   2   0  14  24  24  24  24   8   0   0   0  96   0   0
G |  10   0   8   2   8  24   4   0   2  24  24  24  24  10   0  96   0   0   0   0
T |  70  96  70   4   8  24  84  96  72  24  24  24  24  10  96   0  96   0   0   0

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updated Fri Dec 13 11:15:54 2024