structure name | CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE PRDIII-I REGULATORY ELEMENT OF THE HUMAN INTERFERON-B ENHANCER (Interferon regulatory factor 3) |
reference | Nistal-Villan et al. Mol.Cell 26 703 2007 |
source | Homo sapiens |
experiment | X-ray (resolution=2.31, R-factor=0.185) |
structural superfamily | "Winged helix" DNA-binding domain; |
sequence family | Interferon regulatory factor transcription f; |
multimeric complexes | 1t2k_ABCD 2o6g_EFGH 2pi0_ABCD |
redundant complexes | 1t2k_A 2o6g_H |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | HLRNRSNR |
Estimated binding specificities ?
readout + contact |
A | 12 0 12 0 C | 12 0 12 84 G | 12 0 12 0 T | 60 96 60 12scan! |
Related DNA sequences reported in the literature ?
site | source | matches (E-value) |
---|---|---|
term: IRF-3 | ||
AANNGAAA | PubMed | 2pi0_B(1.87e-03), 2o6g_EFGH(6.46e-04), 2pi0_ABCD(6.19e-04) |
Dendrogram of similar interfaces ?
matrix formatECKT----RGAT--RGHT----RA-- L +---4mhg_A +-1 --KT----RG----RGYT-------- L +------------------------2 +---4bqa_A ! ! --KT----RG----RGYA-------- L +-3 +----4l18_B ! ! ------NAST--RGHT--ST------ L +-4 +-----------------------------2uzk_A ! ! ----NAST----RTHT--ST------ L --5 +-----------------------------3l2c_A ! ----NAST----RGHT--STLT--KA L +-----------------------------2c6y_A |
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updated Fri Sep 13 16:35:59 2024