| structure name | HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE INDENOISOQUINOLINE AI-III-52 AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX (DNA topoisomerase I) |
| reference | Ioanoviciu et al. J.Med.Chem. 48 4803 2005 |
| source | Homo sapiens |
| experiment | X-ray (resolution=3.10, R-factor=?) |
| structural superfamily | Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment;DNA breaking-rejoining enzymes;Eukaryotic DNA topoisomerase I, dispensable insert domain; |
| sequence family | Eukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti; |
| reference complex | 1a31_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | ERIYMKNKN |
Estimated binding specificities ?
| contact |  |
A | 19 96 10 9 0 C | 9 0 67 9 0 G | 57 0 0 9 0 T | 11 0 19 69 96scan! |
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updated Mon Dec 18 06:08:47 2023