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structure nameSTRUCTURE OF THE BIPARTITE DNA-BINDING DOMAIN OF TC3 TRANSPOSASE BOUND TO TRANSPOSON DNA
(transposable element tc3 transposase)
referencevan Pouderoyen et al. 'Nucleic 32 4306 2004
sourceCaenorhabditis elegans
experimentX-ray (resolution=2.69, R-factor=0.235)
structural superfamilyHomeodomain-like;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePRHSRHRRRSKRTLN

Estimated binding specificities ?

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# IC=18.207 IC/col=0.910 n_of_columns=20 specificity:   
A |   9   4   0  74  77  24   9   0  24  24   0  96   4  96   0   0  77   0   0   3
C |   4   0   0   9   6  24   1   3  24  24   3   0   3   0   0   0   6  96  96  89
G |  80  89  96   7   7  24  83   1  24  24   0   0   3   0  96  96   7   0   0   4
T |   3   3   0   6   6  24   3  92  24  24  93   0  86   0   0   0   6   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------KG----ECRG--HC--KTPT----STQAQGAT--SA----   L             +-----------------------------4u7b_B    
                                                                 +-1 
  NG--SCHG------SGKT------SA------SG--SGSG--NART--   L         +-2 +-----------------------------1k78_A    
                                                               ! ! 
  ----STNT--CT--ST--------------RGSGVTSCSG--NTRTRT   L       +-3 +-----------------------------6pax_A    
                                                             ! ! 
  --------TG--RTDC--YT------------SGRAAA----FT----   L     +-4 +-----------------------------4fcy_B    
                                                           ! ! 
  RTHGSGRGHG----RT--------------------------------   L   +-5 +-----------------------------1tc3_C    
                                                         ! ! 
  --------------IT----IT----RTPA--AGLASTTGLT--KA--   L --6 +-----------------------------4m6f_A    
                                                         ! 
  ----------------IT----FT--RA----ACRGSGTC--YTKT--   L   +-----------------------------1gdt_A    
                                                       

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updated Fri Sep 13 16:04:26 2024