1u8r_GHIJ : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN IDER-DNA COMPLEX REVEALS A CONFORMATIONAL CHANGE IN ACTIVATED IDER FOR BASE-SPECIFIC INTERACTIONS
reference	Wisedchaisri et al. J.Mol.Biol. 342 1155 2004
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=2.75, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;C-terminal domain of transcriptional repressors;
reference complex	1u8r_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1u8r_G interface=37,39,40,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvglvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_H interface=37,39,40,42,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvgnlvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_I interface=37,39,40,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvglvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_J interface=37,39,40,42,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvgnlvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv
interface signature	SPTQR/SPTSQR/SPTQR/SPTSQR

Estimated binding specificities ?

contact

# IC=17.654 IC/col=1.038 n_of_columns=17

specificity:

A |   2  11  96   9   2  96   7  96   0   0   0   0   9   0   0   9   0
C |   4   9   0  11  90   0  68   0   0   0  96   0   8  96  96  69   0
G |   2   9   0  69   2   0  12   0  96  96   0   0  67   0   0   9   0
T |  88  67   0   7   2   0   9   0   0   0   0  96  12   0   0   9  96

scan!

home
updated Tue Jul 29 16:59:04 2025