1u8r_GHIJ : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN IDER-DNA COMPLEX REVEALS A CONFORMATIONAL CHANGE IN ACTIVATED IDER FOR BASE-SPECIFIC INTERACTIONS
reference	Wisedchaisri et al. J.Mol.Biol. 342 1155 2004
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=2.75, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	2isz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1u8r_G interface=37,39,40,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvglvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_H interface=37,39,40,42,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvgnlvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_I interface=37,39,40,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvglvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_J interface=37,39,40,42,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvgnlvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv
interface signature	SPTQR/SPTSQR/SPTQR/SPTSQR

Estimated binding specificities ?

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# IC=17.636 IC/col=1.037 n_of_columns=17

specificity:

A |   2  12  96  11   4  96  11  96   0   0   0   0   8   0   0   7   0
C |   2   9   0   9  88   0  67   0   0   0  96   0   9  96  96  69   0
G |   2   8   0  69   2   0   9   0  96  96   0   0  67   0   0   9   0
T |  90  67   0   7   2   0   9   0   0   0   0  96  12   0   0  11  96

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updated Sun Jan 4 23:49:52 2026