1u8r_GHIJ : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN IDER-DNA COMPLEX REVEALS A CONFORMATIONAL CHANGE IN ACTIVATED IDER FOR BASE-SPECIFIC INTERACTIONS
reference	Wisedchaisri et al. J.Mol.Biol. 342 1155 2004
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=2.75, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	2isz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1u8r_G interface=37,39,40,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvglvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_H interface=37,39,40,42,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvgnlvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_I interface=37,39,40,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvglvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv > 1u8r_J interface=37,39,40,42,43,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipgldelgvgnlvrltelpagspvavvvrqltehvqgdidlitrlkdagvvpnarvtvettpgggvtivipghenvtlphemahavkvekv
interface signature	SPTQR/SPTSQR/SPTQR/SPTSQR

Estimated binding specificities ?

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# IC=17.897 IC/col=1.053 n_of_columns=17

specificity:

A |   2  12  96   9   2  96   4  96   0   0   0   0   7   0   0   9   0
C |   2   7   0   9  88   0  73   0   0   0  96   0   9  96  96  73   0
G |   4   9   0  69   2   0  12   0  96  96   0   0  71   0   0   7   0
T |  88  68   0   9   4   0   7   0   0   0   0  96   9   0   0   7  96

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updated Wed Jun 24 11:51:18 2026