interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM I
(Iron-dependent repressor ideR)
referenceWisedchaisri et al. Biochemistry 46 436 2007
sourceMycobacterium tuberculosis
experimentX-ray (resolution=2.40, R-factor=0.201)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
sequence familyIron dependent repressor, metal bindin; Iron dependent repressor, Nterminal D; MarR family;
multimeric complexes1u8r_ABCD 1u8r_GHIJ 2isz_ABCD 2it0_ABCD
redundant complexes1u8r_D 2it0_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQRR

Estimated binding specificities ?

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# IC=4.963 IC/col=0.827 n_of_columns=6 specificity:   
A |   6   9  75   6   0   0
C |   6   6   6   6   0   6
G |   9   6   6  78  96  90
T |  75  75   9   6   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --QT--PTAT--TT------------YT----                               +8pw0_A    
                                                      +----------1 
  ------RGSTRTSTHG--------RA------   L                !          +3zpl_B    
                                                +-----3 
  ----------------YG--------------              !     !       +--3eyi_B    
                                         +------4     +-------2 
  --------------RCYG----KT--------       !      !             +--2acj_B    
                                       --5      ! 
  TT------KATTQTTGLTRTKA------FTYT   L   !      +----------------2p7c_B    
                                         ! 
  ----DCLT--AGTTRG--RG------------   L   +-----------------------5h3r_A    
                                       

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updated Mon Jun 29 15:17:25 2026