interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM I
(Iron-dependent repressor ideR)
referenceWisedchaisri et al. Biochemistry 46 436 2007
sourceMycobacterium tuberculosis
experimentX-ray (resolution=2.40, R-factor=0.201)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
sequence familyIron dependent repressor, metal bindin; Iron dependent repressor, Nterminal D; MarR family;
multimeric complexes2isz_ABCD 2it0_ABCD
redundant complexes2it0_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQRR

Estimated binding specificities ?

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# IC=4.865 IC/col=0.811 n_of_columns=6 specificity:   
A |   9   6  75   6   0   0
C |   6   9   6   9   0   7
G |   6   6   9  75  96  89
T |  75  75   6   6   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --QT--PTAT--TT----------YT----                                 +8pw0_A    
                                                 +---------------1 
  ------RGSTRTSTHG------RA------   L       +-----2               +3zpl_B    
                                           !     ! 
  ----DCLT--AGTTRG--RG----------   L     +-3     +---------------5h3r_A    
                                         ! ! 
  TT------KATTQTTGLTRTKA----FTYT   L   +-4 +---------------------2p7c_B    
                                       ! ! 
  ----SG--PTPGTT----------HG----   L --5 +-----------------------7d98_Q    
                                       ! 
  ----------------YG------------       +-------------------------3eyi_B    
                                     

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updated Tue Dec 17 22:52:01 2024