interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM I
(Iron-dependent repressor ideR)
referenceWisedchaisri et al. Biochemistry 46 436 2007
sourceMycobacterium tuberculosis
experimentX-ray (resolution=2.40, R-factor=0.201)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
sequence familyIron dependent repressor, metal bindin; Iron dependent repressor, Nterminal D; MarR family;
multimeric complexes2isz_ABCD 2it0_ABCD
redundant complexes2it0_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQRR

Estimated binding specificities ?

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# IC=5.007 IC/col=0.835 n_of_columns=6 specificity:   
A |   0   0   6   9  78  75
C |  89  96  78   6   6   6
G |   7   0   6   6   6   9
T |   0   0   6  75   6   6
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --QT--PTAT--TT----------YT----                                 +8pw0_A    
                                                 +---------------1 
  ------RGSTRTSTHG------RA------   L       +-----2               +3zpl_B    
                                           !     ! 
  ----DCLT--AGTTRG--RG----------   L     +-3     +---------------5h3r_A    
                                         ! ! 
  TT------KATTQTTGLTRTKA----FTYT   L   +-4 +---------------------2p7c_B    
                                       ! ! 
  ----SG--PTPGTT----------HG----   L --5 +-----------------------7d98_Q    
                                       ! 
  ----------------YG------------       +-------------------------3eyi_B    
                                     

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updated Sun Aug 3 06:19:26 2025