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structure nameTHE GCN4 BASIC REGION LEUCINE ZIPPER BINDS DNA AS A DIMER OF UNINTERRUPTED ALPHA HELICES: CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX
(PROTEIN GCN4)
referenceEllenberger et al.
sourceSACCHAROMYCES CEREVISIAE
experimentX-ray (resolution=2.90, R-factor=0.230)
structural superfamilyLeucine zipper domain;
sequence familybZIP transcription factor; Basic region leucine zipper;
multimeric complexes1ysa_CD
reference complex2dgc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKNTAAR

Estimated binding specificities ?

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# IC=3.976 IC/col=0.663 n_of_columns=6 specificity:   
A |  81   9   0  88  24  24
C |   7   7   0   0  24   7
G |   1   7  96   8  24  14
T |   7  73   0   0  24  51
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updated Thu Jan 8 19:30:05 2026