1zlk_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS HYPOXIC RESPONSE REGULATOR DOSR C-TERMINAL DOMAIN-DNA COMPLEX
reference	Wisedchaisri et al. J.Mol.Biol. 354 630 2005
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	C-terminal effector domain of the bipartite response regulators;
reference complex	1zlk_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1zlk_A interface=35,36,38,39,40,42, dplsgltdqertllgllsegltnkqiadrmflaeKTvKNYvSrllaklgmerrtqaavfatelkr > 1zlk_B interface=35,36,38,39,40,42, dplsgltdqertllgllsegltnkqiadrmflaeKTvKNYvSrllaklgmerrtqaavfatelkr
interface signature	KTKNYS/KTKNYS

Estimated binding specificities ?

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# IC=14.242 IC/col=0.949 n_of_columns=15

specificity:

A |   0   7   0  96   0   9  24  24  73   0   0   0   0   0   7
C |   0   7   0   0  96   7  24  24   7   0   0  96  96  96   9
G |  96  73  96   0   0   7  24  24   7  96   0   0   0   0   7
T |   0   9   0   0   0  73  24  24   9   0  96   0   0   0  73

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updated Mon Jan 5 00:13:42 2026