2c7a_AB : 3D-footprint complex

structure name	STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
reference	Churchill et al. Mol.Endocrinol. 20 3042 2006
source	HOMO SAPIENS
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	2c7a_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2c7a_A interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRkfk > 2c7a_B interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRk
interface signature	KVRR/KVRR

Estimated binding specificities ?

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# IC=10.286 IC/col=0.605 n_of_columns=17

specificity:

A |   5  59   0  24  62   0  96  24  24  24   0   0   7  24   0  24  12
C |  84  12   0  24  12  96   0  24  24  24   0   0  12  24  96  24  11
G |   0  14  96  24  11   0   0  24  24  24   0  96  11  24   0  24  62
T |   7  11   0  24  11   0   0  24  24  24  96   0  66  24   0  24  11

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updated Mon Jan 5 00:18:41 2026