2c7a_AB : 3D-footprint complex

structure name	STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
reference	Churchill et al. Mol.Endocrinol. 20 3042 2006
source	HOMO SAPIENS
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2c7a_A interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRkfk > 2c7a_B interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRk
interface signature	KVRR/KVRR

Estimated binding specificities ?

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# IC=10.186 IC/col=0.599 n_of_columns=17

specificity:

A |   3  58   0  24  65   0  96  24  24  24   3   0  10  24   0  24  10
C |  85  10   0  24  10  96   0  24  24  24   1   0  10  24  96  24  10
G |   2  10  96  24  10   0   0  24  24  24   0  96  11  24   0  24  65
T |   6  18   0  24  11   0   0  24  24  24  92   0  65  24   0  24  11

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updated Fri Dec 13 11:49:39 2024