2c7a_AB : 3D-footprint complex

structure name	STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
reference	Churchill et al. Mol.Endocrinol. 20 3042 2006
source	HOMO SAPIENS
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2c7a_A interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRkfk > 2c7a_B interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRk
interface signature	KVRR/KVRR

Estimated binding specificities ?

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# IC=12.209 IC/col=0.718 n_of_columns=17

specificity:

A |   3  62   0  87  88   0  88  24  24  24   0   0   7  24   0  24   3
C |  85  10   0   3   3  96   5  24  24  24   0   0  11  24  96  24   3
G |   3  14  96   3   5   0   0  24  24  24   0  96  14  24   0  24  87
T |   5  10   0   3   0   0   3  24  24  24  96   0  64  24   0  24   3

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updated Tue Jul 29 17:24:15 2025