2c7a_AB : 3D-footprint complex

structure name	STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
reference	Churchill et al. Mol.Endocrinol. 20 3042 2006
source	HOMO SAPIENS
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2c7a_A interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRkfk > 2c7a_B interface=26,27,31,75, pqkiclicgdeasgchygvltcgscKVffkRamegqhnylcagrndcivdkirrkncpacrlrkccqagmvlggRk
interface signature	KVRR/KVRR

Estimated binding specificities ?

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# IC=12.233 IC/col=0.720 n_of_columns=17

specificity:

A |   5  64   0  85  88   0  88  24  24  24   0   0   7  24   0  24   3
C |  85  14   0   3   5  96   5  24  24  24   0   0  14  24  96  24   5
G |   3  11  96   0   3   0   0  24  24  24   0  96   8  24   0  24  85
T |   3   7   0   8   0   0   3  24  24  24  96   0  67  24   0  24   3

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updated Mon Sep 9 14:48:22 2024