interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
(PROGESTERONE RECEPTOR)
referenceChurchill et al. Mol.Endocrinol. 20 3042 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=2.50, R-factor=0.203)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes2c7a_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVRR

Estimated binding specificities ?

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# IC=4.960 IC/col=0.709 n_of_columns=7 specificity:   
A |   0   0   9  24   7   7   7
C |   0   0   7  24  75   7   7
G |   0  96   7  24   7   9  73
T |  96   0  73  24   7  73   9
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --ECKGAGKGRG   L       +-----------------------------8cef_H    
                       +-1 
  HAECKG--RGRG   L   +-2 +-----------------------------1a6y_A    
                     ! ! 
  --ETKGAT--RG   L --3 +-----------------------------1lat_A    
                     ! 
  --EAKG--KTRG   L   +-----------------------------2han_A    
                   

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updated Mon Jun 29 14:58:57 2026