interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF ACTIVATED NOTCH, CSL AND MAML ON HES-1 PROMOTER DNA SEQUENCE
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF...)
referenceBlacklow et al. 'Cell(Cambridge,Mass.)' 124 973 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=3.25, R-factor=0.241)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKSQ

Estimated binding specificities ?

contactlogo
# IC=7.380 IC/col=0.923 n_of_columns=8 specificity:   
A |   5   5   0   6   5   6  96  85
C |   5   5   0   5  15   5   0   5
G |   5  81   0  85  66  85   0   5
T |  81   5  96   0  10   0   0   1
scan!

home
updated Thu Sep 12 16:05:17 2024