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legend  pdf

structure nameI-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY
referenceHavranek et al. Nature 441 656 2006
sourceMonomastix sp.
experimentX-ray (resolution=2.00, R-factor=?)
structural superfamilyHoming endonucleases;
reference complex2fld_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLRDYQINRRDIDR/SYLIRDYQINRRDIDR

Estimated binding specificities ?

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# IC=20.296 IC/col=0.923 n_of_columns=22 specificity:   
A |   6   0  24  24   4   0   0   0   0   6  24  24   4   0  96   0   0   4  91   0   0   0
C |   4   0  24  24  73   0   0   0  96   4  24  24  82   0   0  96  96   4   0  96   0   0
G |  82  78  24  24  10  96  96   0   0   9  24  24   4  96   0   0   0   6   0   0   0  96
T |   4  18  24  24   9   0   0  96   0  77  24  24   6   0   0   0   0  82   5   0  96   0
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updated Mon Jan 5 00:38:07 2026