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structure nameI-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY
referenceHavranek et al. Nature 441 656 2006
sourceMonomastix sp.
experimentX-ray (resolution=2.00, R-factor=?)
structural superfamilyHoming endonucleases;
reference complex2fld_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLRDYQINRRDIDR/SYLIRDYQINRRDIDR

Estimated binding specificities ?

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# IC=20.345 IC/col=0.925 n_of_columns=22 specificity:   
A |   0  96   0   6  80   0   0   0   0   6  24  24  85   0  96   0   0   5  24  24  16   5
C |  96   0   0   0   5   0   0   0  96   5  24  24   0   0   0  96  96  12  24  24  80  74
G |   0   0  96   0   6  96  96   0   0  80  24  24   0  96   0   0   0  74  24  24   0  12
T |   0   0   0  90   5   0   0  96   0   5  24  24  11   0   0   0   0   5  24  24   0   5
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updated Tue Jul 29 17:41:02 2025