interface graph thumbnail
legend  pdf

structure nameALTERATION OF SEQUENCE SPECIFICITY OF THE TYPE II RESTRICTION ENDONUCLEASE HINCII THROUGH AN INDIRECT READOUT MECHANISM
referenceBitinaite et al. J.Biol.Chem. 281 23852 2006
sourceHaemophilus influenzae
experimentX-ray (resolution=1.83, R-factor=?)
structural superfamilyRestriction endonuclease-like;
reference complex2gig_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQNSFPNYNAAAQQ/SFPNYNAAAQQ

Estimated binding specificities ?

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# IC=7.918 IC/col=0.990 n_of_columns=8 specificity:   
A |  12   0   0   1  11  85  11  10
C |  10   0   0  85   0   1  85  85
G |  64  96   0   0  85   0   0   0
T |  10   0  96  10   0  10   0   1
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updated Tue Jul 29 17:43:01 2025