| structure name | STRUCTURE OF VARIOLA TOPOISOMERASE NON-COVALENTLY BOUND TO DNA (DNA topoisomerase 1) |
| reference | Van Duyne et al. Mol.Cell 23 343 2006 |
| source | Variola virus |
| experiment | X-ray (resolution=1.90, R-factor=0.199) |
| structural superfamily | DNA breaking-rejoining enzymes;DNA topoisomerase I domain; |
| sequence family | Eukaryotic DNA topoisomerase I, catal; Viral DNA topoisomerase I, Nterminal; |
| redundant complexes |  2h7f_X
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RQYYRKKYKDERY |
Estimated binding specificities ?
readout + contact |  |
A | 8 12 20 23 7 10 0 0 0 9 C | 7 12 20 31 7 66 96 96 0 9 G | 7 60 20 21 74 10 0 0 0 11 T | 74 12 36 21 8 10 0 0 96 67scan! |
Dendrogram of similar interfaces ?
matrix formatHTRA--QAYCYT--RT------KGKGYGKT----ETRGYG L +-----------2h7g_X +---------1 ----MG--YA--KT--------NC----KTDA----TT-- L +-----2 +-----------2b9s_A ! ! ----------------RG--------------RG------ L --3 +---------------------3m4a_A ! ------------------FCKC------KC------NTRG L +---------------------------1flo_A |
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updated Sat Jan 10 05:15:46 2026