2hap_CD : 3D-footprint complex

structure name	STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION
reference	Marmorstein et al. Nat.Struct.Biol. 6 22 1999
source	Saccharomyces cerevisiae
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Leucine zipper domain;Zn2/Cys6 DNA-binding domain;
reference complex	2hap_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2hap_C interface=9,17,18, rkrnriplRcticrkrKVkcdklrphcqqctktgvahlchymeqtwaeeaekellkdnelkklrervkslektlsk > 2hap_D interface=2,4,8,15,16,17, kRnRiplRcticrkRKVkcdklrphcqqctktgvahlchymeqtwaeeaekellkdnelkklrervkslektlsk
interface signature	RKV/RRRRKV

Estimated binding specificities ?

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# IC=11.243 IC/col=0.937 n_of_columns=12

specificity:

A |   6   0   0  18  24   6   0  96   0   6   0   6
C |  84   0  96  12  24  12   0   0   0  84   0  84
G |   6  96   0  12  24  18   0   0   0   6  96   0
T |   0   0   0  54  24  60  96   0  96   0   0   6

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updated Fri Dec 13 12:11:28 2024