interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION
(PROTEIN HEME ACTIVATOR PROTEIN)
referenceMarmorstein et al. Nat.Struct.Biol. 6 22 1999
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.50, R-factor=0.248)
structural superfamilyLeucine zipper domain;Zn2/Cys6 DNA-binding domain;
sequence familyFungal Zn2Cys6 binuclear cluster domain;
multimeric complexes2hap_CD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRRRKV

Estimated binding specificities ?

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# IC=7.419 IC/col=0.824 n_of_columns=9 specificity:   
A |   8   0   0  14  24   9   0  96   1
C |  81   0  96  17  24  14   0   0   7
G |   7  96   0  14  24  14   0   0   7
T |   0   0   0  51  24  59  96   0  81
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updated Fri Sep 13 16:20:36 2024