2is2_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF UVRD-DNA BINARY COMPLEX (DNA helicase II)
reference	Lee et al. 'Cell(Cambridge,Mass.)' 127 1349 2006
source	Escherichia coli
experiment	X-ray (resolution=3.00, R-factor=0.229)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	UvrD/REP helicase;
multimeric complexes	2is2_AB 2is4_AB 2is6_AB
reference complex	2is6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2is2_B interface=420,452,617, dvsylldslndkqreavaaprsnllvlagagsgktrvlvhriawlmsvencspysimavtftnkaaaemrhrigqlmgtsqggmwvgtfhglahrllrahhmdanlpqdfqildsedqlrllkrlikamnldekqwpprqamwyinsqkdeglrphhiqsygnpveqtwqkvyqayqeacdraglvdfaelllrahelwlnkphilqhyrerftnilvdefqdtnniqyawirllagdtgkvmivgdddqsiygwrgaqveniqrflndfpgaetirleqnyrstsnilsaanaliennngrlgkklwtdgadgepislycafneldearfvvnriktwqdnggalaecailyrsnaqsrvleeallqasmpyriyggmrfferqeikdalsylrlivnrnddaafervvntptrgigdRtldvvrqtsrdrqltlwqacrellqekalagRaasalqrfmelidalaqetadmplhvqtdrvikdsglrtmyeqekgekgqtrienleelvtatrqfsydedlmplqaflshaaleagegqadtwqdavqlmtlhsakglefpqvfivgmeegmfpsqmsldeggrleeerrlayvgvtramqkltltyaetrrlYgkevyhrpsrfigelpeecveevrl
interface signature	RRY

Estimated binding specificities ?

contact

# IC=3.782 IC/col=0.252 n_of_columns=15

specificity:

A |  17   8  24   0  17  24  24  24  24  24  24  24  24  24   0
C |  61   8  24   0  17  24  24  24  24  24  24  24  24  24   0
G |  10  72  24  96   8  24  24  24  24  24  24  24  24  24  96
T |   8   8  24   0  54  24  24  24  24  24  24  24  24  24   0

scan!

home
updated Thu Jan 8 20:12:24 2026