2is2_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF UVRD-DNA BINARY COMPLEX (DNA helicase II)
reference	Lee et al. 'Cell(Cambridge,Mass.)' 127 1349 2006
source	Escherichia coli
experiment	X-ray (resolution=3.00, R-factor=0.229)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
sequence family	UvrD/REP helicase;
multimeric complexes	2is2_AB 2is4_AB 2is6_AB
reference complex	2is6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2is2_B interface=420,452,617, dvsylldslndkqreavaaprsnllvlagagsgktrvlvhriawlmsvencspysimavtftnkaaaemrhrigqlmgtsqggmwvgtfhglahrllrahhmdanlpqdfqildsedqlrllkrlikamnldekqwpprqamwyinsqkdeglrphhiqsygnpveqtwqkvyqayqeacdraglvdfaelllrahelwlnkphilqhyrerftnilvdefqdtnniqyawirllagdtgkvmivgdddqsiygwrgaqveniqrflndfpgaetirleqnyrstsnilsaanaliennngrlgkklwtdgadgepislycafneldearfvvnriktwqdnggalaecailyrsnaqsrvleeallqasmpyriyggmrfferqeikdalsylrlivnrnddaafervvntptrgigdRtldvvrqtsrdrqltlwqacrellqekalagRaasalqrfmelidalaqetadmplhvqtdrvikdsglrtmyeqekgekgqtrienleelvtatrqfsydedlmplqaflshaaleagegqadtwqdavqlmtlhsakglefpqvfivgmeegmfpsqmsldeggrleeerrlayvgvtramqkltltyaetrrlYgkevyhrpsrfigelpeecveevrl
interface signature	RRY

Estimated binding specificities ?

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# IC=4.064 IC/col=0.271 n_of_columns=15

specificity:

A |   0  24  24  24  24  24  24  24  24  24  36   0  24   0   8
C |  96  24  24  24  24  24  24  24  24  24  17  96  24  88   8
G |   0  24  24  24  24  24  24  24  24  24  17   0  24   8  54
T |   0  24  24  24  24  24  24  24  24  24  26   0  24   0  26

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updated Sun Jun 28 05:47:23 2026