2isz_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM I
reference	Wisedchaisri et al. Biochemistry 46 436 2007
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	2isz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2isz_A interface=37,39,40,43,47,60, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv > 2isz_B interface=37,39,40,42,43,47,60, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv > 2isz_C interface=37,39,40,47,60, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsqtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv > 2isz_D interface=37,39,40,42,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSqtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv
interface signature	SPTQRR/SPTSQRR/SPTRR/SPTSR

Estimated binding specificities ?

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# IC=15.681 IC/col=0.922 n_of_columns=17

specificity:

A |   1  11  90  11   0   1  24  96   0   0   0   0  17   3  24   1   0
C |   1  17   4   0   0   1  24   0   0  96  96   0  13  11  24  90   0
G |   4  13   1  84  96  90  24   0  96   0   0   0  55   6  24   4   0
T |  90  55   1   1   0   4  24   0   0   0   0  96  11  76  24   1  96

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updated Mon Sep 9 15:17:01 2024