2isz_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM I
reference	Wisedchaisri et al. Biochemistry 46 436 2007
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	2isz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2isz_A interface=37,39,40,43,47,60, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv > 2isz_B interface=37,39,40,42,43,47,60, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv > 2isz_C interface=37,39,40,47,60, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvsqtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv > 2isz_D interface=37,39,40,42,47, mnelvdttemylrtiydleeegvtplrariaerldqSgPTvSqtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgv
interface signature	SPTQRR/SPTSQRR/SPTRR/SPTSR

Estimated binding specificities ?

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# IC=15.514 IC/col=0.913 n_of_columns=17

specificity:

A |   1  15  91   3   0   1  24  96   0   0   0   0  13   9  24   6   3
C |   0  15   1   0   0   1  24   0   0  96  96   0   3  13  24  72   0
G |   3   3   3  93  96  93  24   0  96   0   0   0  65  13  24   9   1
T |  92  63   1   0   0   1  24   0   0   0   0  96  15  61  24   9  92

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updated Fri Dec 13 12:19:55 2024