2it0_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TWO-DOMAIN IDER-DNA COMPLEX CRYSTAL FORM II
reference	Wisedchaisri et al. Biochemistry 46 436 2007
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	2isz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2it0_A interface=35,37,38,41,45,58, elvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgvasenlyf > 2it0_B interface=35,37,38,40,41,45, elvdttemylrtiydleeegvtplrariaerldqSgPTvSQtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelgvasenlyf > 2it0_C interface=35,37,38,41,45,58, elvdttemylrtiydleeegvtplrariaerldqSgPTvsQtvsRmerdgllrvagdRhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelg > 2it0_D interface=35,37,38,40,45, elvdttemylrtiydleeegvtplrariaerldqSgPTvSqtvsRmerdgllrvagdrhleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnnpttspfgnpipglvelg
interface signature	SPTQRR/SPTSQR/SPTQRR/SPTSR

Estimated binding specificities ?

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# IC=12.451 IC/col=0.830 n_of_columns=15

specificity:

A |  96  11  24  24   5  96   0   0   0   5  24  11   0   0   5
C |   0   5  24  24  73   0   0   0  96   5  24  73  96  96   7
G |   0  69  24  24   5   0  96  96   0   5  24   7   0   0   5
T |   0  11  24  24  13   0   0   0   0  81  24   5   0   0  79

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updated Wed Jun 24 12:55:45 2026