interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF E. COLI TOPOISOMERSAE III IN COMPLEX WITH AN 8-BASE SINGLE STRANDED OLIGONUCLEOTIDE. FROZEN IN GLYCEROL AT PH 5.5
(DNA topoisomerase 3)
referenceMondragon et al. J.Mol.Biol. 368 105 2007
sourceEscherichia coli
experimentX-ray (resolution=2.45, R-factor=0.214)
structural superfamilyProkaryotic type I DNA topoisomerase;
sequence familyDNA topoisomerase; Toprim domain;
reference complex2o5c_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHQPWRRDWIRRVQRAT

Estimated binding specificities ?

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# IC=5.664 IC/col=0.708 n_of_columns=8 specificity:   
A |   0   0   0  24  52   9   9   7
C |  96   0  96  24  14  67  11   7
G |   0  96   0  24  14  11   9   7
T |   0   0   0  24  16   9  67  75
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updated Mon Dec 16 19:52:48 2024