2o6g_EFGH : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	Homo sapiens
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	2o6g_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o6g_E interface=40,76,77,79,80,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvns > 2o6g_F interface=37,39,75,76,78,79,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o6g_G interface=38,40,76,77,79,80,81,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvns > 2o6g_H interface=37,39,75,76,78,79,80,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvn
interface signature	LRNRSR/HLRNRSR/HLRNRSAR/HLRNRSAR

Estimated binding specificities ?

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# IC=20.204 IC/col=0.918 n_of_columns=22

specificity:

A |   1   7  24  78  24   1   0   0   0   0   4  11   0   3   0  73  24   0   0   0   0   0
C |   3  11  24   7  24   4   2   0  94  96  86   3   5   1  96   7  24   0  21   0  96  96
G |   6   7  24   5  24   1   0   0   1   0   3   3   1   1   0   7  24   0   1   0   0   0
T |  86  71  24   6  24  90  94  96   1   0   3  79  90  91   0   9  24  96  74  96   0   0

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updated Mon Jan 5 01:24:11 2026