2o6g_EFGH : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	Homo sapiens
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	2pi0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o6g_E interface=40,76,77,79,80,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvns > 2o6g_F interface=37,39,75,76,78,79,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o6g_G interface=38,40,76,77,79,80,81,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvns > 2o6g_H interface=37,39,75,76,78,79,80,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvn
interface signature	LRNRSR/HLRNRSR/HLRNRSAR/HLRNRSAR

Estimated binding specificities ?

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# IC=19.990 IC/col=0.909 n_of_columns=22

specificity:

A |   0   0  96  61  96  24   3   0  84  88  67   4   0   0  96  96  92  24   8  24  76  91
C |   0   0   0   1   0  24   3   0   3   0   3   3   0   1   0   0   2  24   9  24   3   1
G |  96  96   0  34   0  24  10  94   5   7   5  84  96  94   0   0   1  24   5  24   5   1
T |   0   0   0   0   0  24  80   2   4   1  21   5   0   1   0   0   1  24  74  24  12   3

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updated Mon Sep 9 15:43:31 2024