2o6g_EFGH : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	Homo sapiens
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	2pi0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o6g_E interface=40,76,77,79,80,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvns > 2o6g_F interface=37,39,75,76,78,79,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o6g_G interface=38,40,76,77,79,80,81,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvns > 2o6g_H interface=37,39,75,76,78,79,80,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvn
interface signature	LRNRSR/HLRNRSR/HLRNRSAR/HLRNRSAR

Estimated binding specificities ?

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# IC=20.328 IC/col=0.924 n_of_columns=22

specificity:

A |   3   5  24  72  24   0   0   0   0   0   4  18   1   1   1  74  24   0   0   0   0   0
C |   3   9  24   5  24   0   0   0  96  96  84   5   5   3  94  12  24   0  33   0  96  96
G |   1   8  24   9  24   0   0   0   0   0   3   3   0   0   0   7  24   0   1   0   0   0
T |  89  74  24  10  24  96  96  96   0   0   5  70  90  92   1   3  24  96  62  96   0   0

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updated Tue Jul 29 18:22:48 2025