2o6g_EFGH : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE INTERFERON-B ENHANCER
reference	'Cell(Cambridge,Mass.)' 129 1111 2007
source	Homo sapiens
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	2o6g_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2o6g_E interface=40,76,77,79,80,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkhgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvns > 2o6g_F interface=37,39,75,76,78,79,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefvn > 2o6g_G interface=38,40,76,77,79,80,81,84, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvns > 2o6g_H interface=37,39,75,76,78,79,80,83, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSAlnRkeglrlaedrskdphdphkiyefvn
interface signature	LRNRSR/HLRNRSR/HLRNRSAR/HLRNRSAR

Estimated binding specificities ?

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# IC=19.992 IC/col=0.909 n_of_columns=22

specificity:

A |   0   0  96  71  96  24   4   0  84  84  75   4   0   0  96  91  88  24   4  24  87  87
C |   0   0   0   0   0  24   6   0   6   0   4   6   0   2   0   1   4  24   4  24   4   5
G |  96  96   0  24   0  24   6  93   2  12   6  82  96  94   0   4   2  24   6  24   3   2
T |   0   0   0   1   0  24  80   3   4   0  11   4   0   0   0   0   2  24  82  24   2   2

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updated Wed Jun 24 13:24:38 2026