2pi0_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE PRDIII-I REGULATORY ELEMENT OF THE HUMAN INTERFERON-B ENHANCER
reference	Nistal-Villan et al. Mol.Cell 26 703 2007
source	Homo sapiens
experiment	X-ray (resolution=2.31, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2pi0_A interface=36,66,67,69,70,74, kprilpwlvsqldlgqlegvawvnksrtrfripwkHglrgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefv > 2pi0_B interface=40,42,78,79,81,82,85,86, mgtpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalNRkeglrlaedrskdphdphkiyefvns > 2pi0_C interface=37,39,75,76,78,79, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnrkeglrlaedrskdphdphkiyefv > 2pi0_D interface=38,40,71,72,74,75,76,78,79, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdagifqawaeatgayvpgrdkpdlptwkRNfRSAlNRkeglrlaedrskdphdphkiyefvn
interface signature	HRNRSR/HLRNRSNR/HLRNRS/HLRNRSANR

Estimated binding specificities ?

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# IC=24.637 IC/col=0.948 n_of_columns=26

specificity:

A |   0   1  24  94  96  94  24   3   0  96  96  96   0   0   0  61   1  86  24  24   1  24  82  96  95   3
C |   0   1  24   1   0   0  71   3   0   0   0   0   0   0   0   7   0   4  24  24   1  24   0   0   1   0
G |  96  86  24   1   0   1   1   4  96   0   0   0  32  96  96  19  94   5  24  24   8  24  14   0   0  92
T |   0   8  24   0   0   1   0  86   0   0   0   0  64   0   0   9   1   1  24  24  86  24   0   0   0   1

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updated Fri Dec 13 12:57:00 2024