2pi0_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE PRDIII-I REGULATORY ELEMENT OF THE HUMAN INTERFERON-B ENHANCER
reference	Nistal-Villan et al. Mol.Cell 26 703 2007
source	Homo sapiens
experiment	X-ray (resolution=2.31, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	2pi0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2pi0_A interface=36,66,67,69,70,74, kprilpwlvsqldlgqlegvawvnksrtrfripwkHglrgifqawaeatgayvpgrdkpdlptwkRNfRSalnRkeglrlaedrskdphdphkiyefv > 2pi0_B interface=40,42,78,79,81,82,85,86, mgtpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalNRkeglrlaedrskdphdphkiyefvns > 2pi0_C interface=37,39,75,76,78,79, pkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdaqqedfgifqawaeatgayvpgrdkpdlptwkRNfRSalnrkeglrlaedrskdphdphkiyefv > 2pi0_D interface=38,40,71,72,74,75,76,78,79, tpkprilpwlvsqldlgqlegvawvnksrtrfripwkHgLrqdagifqawaeatgayvpgrdkpdlptwkRNfRSAlNRkeglrlaedrskdphdphkiyefvn
interface signature	HRNRSR/HLRNRSNR/HLRNRS/HLRNRSANR

Estimated binding specificities ?

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# IC=24.895 IC/col=0.957 n_of_columns=26

specificity:

A |   0   0   0   0  24  86  24  24   9   0   5   0   0  55   0   0   0   0  78   0   0   0   0  24   1   0
C |  96   0   0  11  24   1  24  24   9  96   5  96  96  41   0   0   0  96   5   1   0   0   1  24  90  96
G |   0   0   0   1  24   8  24  24   7   0   5   0   0   0   0   0   0   0   5  61   0   0   0  24   0   0
T |   0  96  96  84  24   1  24  24  71   0  81   0   0   0  96  96  96   0   8  34  96  96  95  24   5   0

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updated Mon Jan 5 01:34:02 2026