interface graph thumbnail
legend  pdf

structure nameHUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 18-MER RNA/DNA HYBRID
(Ribonuclease H1)
referenceGaidamakov et al. Mol.Cell 28 264 2007
sourceHomo sapiens
experimentX-ray (resolution=2.55, R-factor=?)
structural superfamilyRibonuclease H-like;
sequence familyRNase H;
multimeric complexes2qkb_AB 2qkk_JW 2qkk_NS
reference complex8swb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNNQFWS

Estimated binding specificities ?

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# IC=3.730 IC/col=0.533 n_of_columns=7 specificity:   
A |  19   6   0   1  24  24   6
C |   8   8   0   6  24  24  76
G |  57   6  96   6  24  24   8
T |  12  76   0  83  24  24   6
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updated Mon Dec 16 20:03:26 2024