interface graph thumbnail
legend  pdf

structure nameHUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 18-MER RNA/DNA HYBRID
(Ribonuclease H1)
referenceGaidamakov et al. Mol.Cell 28 264 2007
sourceHomo sapiens
experimentX-ray (resolution=2.55, R-factor=?)
structural superfamilyRibonuclease H-like;
sequence familyRNase H;
multimeric complexes2qkb_AB 2qkk_JW 2qkk_NS 3bsu_ABC 3bsu_FGH
reference complex8swb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNNQFWS

Estimated binding specificities ?

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# IC=4.032 IC/col=0.576 n_of_columns=7 specificity:   
A |  16   7   0   7  24  24   0
C |   7   0   0   0  24  24  82
G |  51   8  96   8  24  24   7
T |  22  81   0  81  24  24   7
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updated Thu Jan 8 20:36:15 2026