interface graph thumbnail
legend  pdf

structure nameHUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 14-MER RNA/DNA HYBRID
(Ribonuclease H1)
referenceGaidamakov et al. Mol.Cell 28 264 2007
sourceHomo sapiens
experimentX-ray (resolution=3.20, R-factor=?)
structural superfamilyRibonuclease H-like;
sequence familyRNase H;
multimeric complexes2qkb_AB 2qkk_JW 2qkk_NS 3bsu_ABC 3bsu_FGH
reference complex8swb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNNQFWS

Estimated binding specificities ?

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# IC=4.041 IC/col=0.674 n_of_columns=6 specificity:   
A |  11   9   0   0  24   2
C |  19   9   0   0  24   9
G |  57  11  96   0  24  76
T |   9  67   0  96  24   9
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updated Thu Jan 8 20:36:22 2026