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structure nameCOEVOLUTION OF A HOMING ENDONUCLEASE AND ITS HOST TARGET SEQUENCE
(INTRON-ENCODED DNA ENDONUCLEASE I-ANII)
referenceMcConnell Smith et al. J.Mol.Biol. 372 1305 2007
sourceEMERICELLA NIDULANS
experimentX-ray (resolution=2.40, R-factor=0.219)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
redundant complexes3eh8_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYSTKYTERRIMRRCSYLYISDAYCKKT

Estimated binding specificities ?

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# IC=17.312 IC/col=0.911 n_of_columns=19 specificity:   
A |   0  30   0   0  96   0   0  11  15  24  24   0   0   0   0  24  96  76  92
C |   0   3   0   0   0   0   0  21  19  24  24   0  96   0   0  24   0  10   1
G |  96  61  96  96   0  96  96  11  19  24  24   0   0   0  96  24   0   3   3
T |   0   2   0   0   0   0   0  53  43  24  24  96   0  96   0  24   0   7   0
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Mon Jun 29 15:35:51 2026