2xcr_BD : 3D-footprint complex

structure name	THE 3.5A CRYSTAL STRUCTURE OF THE CATALYTIC CORE (B'A' REGION) OF STAPHYLOCOCCUS AUREUS DNA GYRASE COMPLEXED WITH GSK299423 AND DNA
reference	Eggleston et al. Nature 466 935 2010
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	2xcr_U
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xcr_B interface=44,311,312,402, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpplykltqgkqkyyvyndreldklkselnptpkwsiarykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavyanldfaelpqsrinernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg > 2xcr_D interface=43,45,313,350,403, gkladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpplykltqgkqkyyvyndreldklkselnptpkwsiarykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavyanldfaelpqsrinernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg
interface signature	KSSI/RKSRI

Estimated binding specificities ?

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# IC=7.185 IC/col=0.513 n_of_columns=14

specificity:

A |   0   0  24  84  16  24  24  24  24   4   6  24   4   0
C |  96   0  24   4  12  24  24  24  24  79  16  24  84   0
G |   0  96  24   4  54  24  24  24  24   9   4  24   4  96
T |   0   0  24   4  14  24  24  24  24   4  70  24   4   0

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updated Mon Sep 9 16:08:00 2024