legend  pdf

interface graphfootprint logointerface matrixatomic interactionsinterface residue numbers

structure name	1.98A STRUCTURE OF GSK945237 WITH S.AUREUS DNA GYRASE AND SINGLY NICKED DNA (DNA GYRASE SUBUNIT A)
reference	Miles et al. Bioorg.Med.Chem.Lett. 26 2464 2016
source	STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315)
experiment	X-ray (resolution=1.98, R-factor=0.166)
structural superfamily	Type II DNA topoisomerase;
sequence family	DNA gyrase/topoisomerase IV, subunit A;
multimeric complexes	2xcr_BD 2xcr_SU 2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5cdo_ABCD 5cdo_RSTU 5cdq_ABCD 5cdq_RSTU 5cdr_AB 5cdr_CD 5iwi_AB 5iwi_CD 5iwm_ABCD 5npk_bd 6fm4_BD 6fqm_ABCD 6fqm_abcd 6fqv_ABCD 6fqv_RSTU 6qtk_ABCD 6qtp_ABCD 6qx1_ABCD 7fvs_AB 7fvt_AB 7mvs_AB
redundant complexes	2xcr_S 2xcs_B 4bul_C 4plb_D 5bs3_D 5cdq_R 5cdr_A 5iwm_C 5npk_d 6fm4_B 6fqv_T 6qx1_A 7fvs_A 7fvt_A 7mvs_B 5cdo 6fqm 6qtk 6qtp
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5iwi_C interface=16,75,76,113,166, nernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql

No structural evidence for specific binding to DNA (<4 informative columns)

Dendrogram of similar interfaces ?