| structure name | 1.98A STRUCTURE OF GSK945237 WITH S.AUREUS DNA GYRASE AND SINGLY NICKED DNA (DNA GYRASE SUBUNIT A) |
| reference | Miles et al. Bioorg.Med.Chem.Lett. 26 2464 2016 |
| source | STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) |
| experiment | X-ray (resolution=1.98, R-factor=0.166) |
| structural superfamily | Type II DNA topoisomerase; |
| sequence family | DNA gyrase/topoisomerase IV, subunit A; |
| multimeric complexes | 2xcr_BD 2xcr_SU 2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5cdo_ABCD 5cdo_RSTU 5cdq_ABCD 5cdq_RSTU 5cdr_AB 5cdr_CD 5iwi_AB 5iwi_CD 5iwm_ABCD 5npk_bd 6fm4_BD 6fqm_ABCD 6fqm_abcd 6fqv_ABCD 6fqv_RSTU 6qtk_ABCD 6qtp_ABCD 6qx1_ABCD 7fvs_AB 7fvt_AB 7mvs_AB |
| redundant complexes | 2xcr_S
2xcs_B
4bul_C
4plb_D
5bs3_D
5cdq_R
5cdr_A
5iwm_C
 5npk_d
6fm4_B
6fqv_T
6qx1_A
7fvs_A
7fvt_A
7mvs_B
5cdo
6fqm
6qtk
6qtp
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix format------------SA------------RG----IG------------------------ +--2xcr_U ! YC----------SG------------RT----IG------------------------ +-------3 +5iwi_C ! ! +-1 ------------SA------------RG----IG--QT-------------------- L ! +--2 +5npk_d +---4 ! ----RC------AT------------------IC--------------RG-------- L ! ! +2xkk_C +-5 ! YT----------ST--------------RA--IG------------------------ ! ! +----------5bs8_A +-6 ! --------------------------------------------------LAECDAKG ! ! +--------------6n1p_A +-7 ! ----RC------ST------------------IA------------------------ ! ! +----------------3ksb_B +-8 ! ------------SA----------------EGIGSC---------------------- ! ! +------------------3l4j_A +------9 ! ----------QAAG------------------IGAG---------------------- L ! ! +--------------------5zen_A +-10 ! --DC--------------------------ECIGSG---------------------- L ! ! +---------------------4fm9_A +-11 ! ------QA--------------------NG---------------------------- ! ! +----------------------------7k63_U +-12 ! --------RC------------------------------------------------ ! ! +----------------------------7cow_T -13 ! --------------NASTRGHTSTLT-------------------------------- L ! +----------------------------7cby_C ! --------------------------------------TAFCAGRCFA---------- L +----------------------------6dg0_A |
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updated Sat Jan 10 08:17:39 2026