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legend  pdf

structure nameMOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
(I-CREI V2V3 VARIANT)
referenceChion-Sotine et al. 'Nucleic 39 729 2011
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.31, R-factor=0.215)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes2xe0_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQNNSRRYTRVQT

Estimated binding specificities ?

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# IC=13.135 IC/col=1.010 n_of_columns=13 specificity:   
A |   0  10   0   0   0   0   0   0  96   2  11  46  90
C |   0  55   0  14   0  96   0   0   0   5  28   2   2
G |   0   8   0  81  96   0   0  96   0  84  49   2   2
T |  96  23  96   1   0   0  96   0   0   5   8  46   2
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Dendrogram of similar interfaces ?

matrix format



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updated Fri Sep 13 16:46:26 2024