2xe0_AB : 3D-footprint complex

structure name	MOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
reference	Chion-Sotine et al. 'Nucleic 39 729 2011
source	CHLAMYDOMONAS REINHARDTII
experiment	X-ray (resolution=2.31, R-factor=?)
structural superfamily	Homing endonucleases;
reference complex	2vbo_A 2xe0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xe0_A interface=21,23,25,27,29,31,37,39,43,45,67,72,74,139, ntkynkefllylagfvdgdgSiIaQiNpNaSskfkhRlRltfYvTqktqrrwfldklvdeigvgyvRdsgsVsQyvlseiaplhnfltqlqpflklkqkqanlvlkiieqlpsakaspaaflevctwvdqiaalndsaTrkttsetvaavld > 2xe0_B interface=21,23,25,27,29,31,32,37,39,43,45,67,69,72,74,76,78,138,139, ntkynkefllylagfvdgdgSiIaQiKpRaSNkfahQlSltfAvTqktqrrwfldklvdeigvgyvYdSgsVsDyRlSeikplhnfltqlqpflklkqkqanlvlaiieqlpsakaspdaflevctwvdqiaalndsKTrattsatvraald
interface signature	SIQNNSRRYTRVQT/SIQKRSNQSATYSVDRSKT

Estimated binding specificities ?

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# IC=23.159 IC/col=1.007 n_of_columns=23

specificity:

A |   0   0   5  24   0   0   0  96   5   5  24  24   5   0   0   0  96   0   0   0  96   5  80
C |   0   0   5  24  96   0  96   0   6   5  24  24  81  96   0  96   0   0  96  96   0   5   5
G |   0  96   5  24   0   0   0   0  80  81  24  24   5   0   0   0   0  96   0   0   0  80   6
T |  96   0  81  24   0  96   0   0   5   5  24  24   5   0  96   0   0   0   0   0   0   6   5

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updated Mon Jan 5 01:56:47 2026