interface graph thumbnail
legend  pdf

structure nameMOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
(I-CREI V2V3 VARIANT)
referenceChion-Sotine et al. 'Nucleic 39 729 2011
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.31, R-factor=0.215)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes2xe0_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKRSNQSATYSVDRSKT

Estimated binding specificities ?

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# IC=10.740 IC/col=0.895 n_of_columns=12 specificity:   
A |   0   0  13  24   0   2   0  93  17   5   5  90
C |   0  14   5  24  96   5  96   1  14   5   2   2
G |   0  81  14  24   0   2   0   0  63  84   2   2
T |  96   1  64  24   0  87   0   2   2   2  87   2
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Dendrogram of similar interfaces ?

matrix format

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updated Fri Sep 13 16:46:39 2024