2xkk_AC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, AND A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)
reference	Shillings et al. Nat.Struct.Mol.Biol. 17 1152 2010
source	ACINETOBACTER BAUMANNII
experiment	X-ray (resolution=3.25, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	2xkk_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xkk_A interface=42,202,290,381,535, alpgkltreeselfivegdsaggsakqardknfqaimpirgKilntwevssdevlasqevhdiaiaigvdpgsddlselrygkiciladadsdglhiatllcalfvkhfpalveeghlyvampplfridigkdvhyalddeeletilknvknpqitrfkglgemnaiqlrettmdpntrrlvqldlddahltaglldkllaKkraadrkqwleqkenrsvaefteqaylnyamyvimdralphisdglkpvqrrivyamselglkssgkpkksartvgdvlgkyhphgdSacyeamvlmaqpfsyrypliegqgnwgspddpksfaamrteaklsayselllselgqgtsewqdnfdgslkepitlparvpnillngttgIavgmatdipphnlrevvkgtialirnpqtsdeklaeyipapdlptkaeiitppeellkiqttgrgsyrmravytiekneivitelpyqvsgskvitqiadqmqakklplvvdvrdesdhenptrlvivlrsnridaeavmshlfattdlessyRvnlnmigedgrpqvksirrillewieirkktvtrrlqyhlnriekrlhilaglliayldidtviriireedqpkpvlmehfnideiqaeailelklrhlakleemeirheqdelsakaaiireqlenpeslknliiselkedakkfgderrspiva > 2xkk_C interface=57,257,309,399,553, erkkivsgpalpgkladcvgqtreeselfivegdsaggsakqardknfqaimpirgKilntwevssdevlasqevhdiaiaigvdpgsddlselrygkiciladadsdglhiatllcalfvkhfpalveeghlyvampplfridigkdvhyalddeeletilknvknpqitrfkglgemnaiqlrettmdpntrrlvqldlddahltaglldkllakkraadrkqwleqkgatenrsvaefteqaylnyamyvimdRalphisdglkpvqrrivyamselglkssgkpkksartvgdvlgkyhphgdsAcyeamvlmaqpfsyrypliegqgnwgspddpksfaamrteaklsayselllselgqgtsewqdnfdgslkepitlparvpnillngttgIavgmatdipphnlrevvkgtialirnpqtsdeklaeyipapdlptkaeiitppeellkiqttgrgsyrmravytiekneivitelpyqvsgskvitqiadqmqakklplvvdvrdesdhenptrlvivlrsnridaeavmshlfattdlessyRvnlnmigedgrpqvksirrillewieirkktvtrrlqyhlnriekrlhilaglliayldidtviriireedqpkpvlmehfnideiqaeailelklrhlakleemeirheqdelsakaaiireqlenpeslknliiselkedakkfgderrspivar
interface signature	KKSIR/KRAIR

Estimated binding specificities ?

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# IC=12.703 IC/col=0.706 n_of_columns=18

specificity:

A |   0  96   0   0  24  76   0  24  24  24  24  78   6  24   0  96   1   6
C |  89   0   0   0  24   8   0  24  24  24  24   6   8  24  96   0  89   6
G |   1   0   0  96  24   6   0  24  24  24  24   6   6  24   0   0   0  76
T |   6   0  96   0  24   6  96  24  24  24  24   6  76  24   0   0   6   8

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updated Wed Jun 24 13:55:36 2026