2xkk_AC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, AND A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)
reference	Shillings et al. Nat.Struct.Mol.Biol. 17 1152 2010
source	ACINETOBACTER BAUMANNII
experiment	X-ray (resolution=3.25, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	2xkk_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xkk_A interface=42,202,290,381,535, alpgkltreeselfivegdsaggsakqardknfqaimpirgKilntwevssdevlasqevhdiaiaigvdpgsddlselrygkiciladadsdglhiatllcalfvkhfpalveeghlyvampplfridigkdvhyalddeeletilknvknpqitrfkglgemnaiqlrettmdpntrrlvqldlddahltaglldkllaKkraadrkqwleqkenrsvaefteqaylnyamyvimdralphisdglkpvqrrivyamselglkssgkpkksartvgdvlgkyhphgdSacyeamvlmaqpfsyrypliegqgnwgspddpksfaamrteaklsayselllselgqgtsewqdnfdgslkepitlparvpnillngttgIavgmatdipphnlrevvkgtialirnpqtsdeklaeyipapdlptkaeiitppeellkiqttgrgsyrmravytiekneivitelpyqvsgskvitqiadqmqakklplvvdvrdesdhenptrlvivlrsnridaeavmshlfattdlessyRvnlnmigedgrpqvksirrillewieirkktvtrrlqyhlnriekrlhilaglliayldidtviriireedqpkpvlmehfnideiqaeailelklrhlakleemeirheqdelsakaaiireqlenpeslknliiselkedakkfgderrspiva > 2xkk_C interface=57,257,309,399,553, erkkivsgpalpgkladcvgqtreeselfivegdsaggsakqardknfqaimpirgKilntwevssdevlasqevhdiaiaigvdpgsddlselrygkiciladadsdglhiatllcalfvkhfpalveeghlyvampplfridigkdvhyalddeeletilknvknpqitrfkglgemnaiqlrettmdpntrrlvqldlddahltaglldkllakkraadrkqwleqkgatenrsvaefteqaylnyamyvimdRalphisdglkpvqrrivyamselglkssgkpkksartvgdvlgkyhphgdsAcyeamvlmaqpfsyrypliegqgnwgspddpksfaamrteaklsayselllselgqgtsewqdnfdgslkepitlparvpnillngttgIavgmatdipphnlrevvkgtialirnpqtsdeklaeyipapdlptkaeiitppeellkiqttgrgsyrmravytiekneivitelpyqvsgskvitqiadqmqakklplvvdvrdesdhenptrlvivlrsnridaeavmshlfattdlessyRvnlnmigedgrpqvksirrillewieirkktvtrrlqyhlnriekrlhilaglliayldidtviriireedqpkpvlmehfnideiqaeailelklrhlakleemeirheqdelsakaaiireqlenpeslknliiselkedakkfgderrspivar
interface signature	KKSIR/KRAIR

Estimated binding specificities ?

contact

# IC=12.705 IC/col=0.706 n_of_columns=18

specificity:

A |   0  96   0   0  24  76   0  24  24  24  24  76   6  24   0  96   0   6
C |  90   0   0   0  24   6   0  24  24  24  24   6   8  24  96   0  89   6
G |   0   0   0  96  24   6   0  24  24  24  24   6   6  24   0   0   1  76
T |   6   0  96   0  24   8  96  24  24  24  24   8  76  24   0   0   6   8

scan!

home
updated Mon Sep 9 16:10:46 2024