2y7h_ABC : 3D-footprint complex

structure name	ATOMIC MODEL OF THE DNA-BOUND METHYLASE COMPLEX FROM THE TYPE I RESTRICTION-MODIFICATION ENZYME ECOKI (M2S1). BASED ON FITTING INTO EM MAP 1534.
reference	Obarska-Kosinska et al. 'Nucleic 37 762 2009
source	ESCHERICHIA COLI
experiment	X-ray (resolution=18.00, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	2y7h_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2y7h_A interface=26,27,70,84,104,145,146,234,236,292,293,294,318,319,357,358, msagklpegwviapvstvttlirgvTYkkeqainylkddylpliranniqngkfdttdlvfvpknlvkeSqkispediviamsSgsksvvgksahqhlpfecsFgafcgvlrpeklifsgfiahftksslyrnkisslsaganiNNikpasfdlinipipplaeqkiiaekldtllaqvdstkarfeqipqilkrfrqavlggavngkltekwrnfepqhsvfkklnfesiltElRnglsskpnesgvghpilrissvraghvdqndirflecseselnrhklqdgdllftRYNgslefvgvcgllkklqhqnllypDKlirarltkdalpeyieiffsspsarnammncvkttsgQKgisgkdiksqvvllppvkeqaeivrrveqlfayadtiekqvnnalarvnnltqsilakafrgeltaqwraenpdlisgensaaallekikaeraasggkkasrkks > 2y7h_B interface=148,266,269,345,350, mnnndlvaklwklcdnlrdggvsyqnyvnelasllflkmcketgqeaeylpegyrwddlksrigqeqlqfyrkmlvhlgeddkklvqavfhnvsttitepkqitalvsnmdsldwyngahgksrddfgdmyegllqknanetksgagQyftprpliktiihllkpqprevvqdpaagtagflieadryvksqtndlddldgdtqdfqihrafiglelvpgtrrlalmncllhdiegnldhggairlgntlgsdgenlpkahivatNppFgsaagtnitrtfvhptsnkqlcfmqhiietlhpggraavvvpdnvlfeggkgtdirrdlmdkchlhtilrlptgiFyaqgVktnvlfftkgtvanpnqdknctddvwvydlrtnmpsfgkrtpftdehlqpfervygedphglsprtegewsfnaeetevadseenkntdqhlatsrwrkfsrewirtaksdsldiswlkdkdsidadslpepdvlaaeamgelvqalseldalmrelgasdeadlqrqlleeafggvke > 2y7h_C interface=148,266,269,345,350,352, mnnndlvaklwklcdnlrdggvsyqnyvnelasllflkmcketgqeaeylpegyrwddlksrigqeqlqfyrkmlvhlgeddkklvqavfhnvsttitepkqitalvsnmdsldwyngahgksrddfgdmyegllqknanetksgagQyftprpliktiihllkpqprevvqdpaagtagflieadryvksqtndlddldgdtqdfqihrafiglelvpgtrrlalmncllhdiegnldhggairlgntlgsdgenlpkahivatNppFgsaagtnitrtfvhptsnkqlcfmqhiietlhpggraavvvpdnvlfeggkgtdirrdlmdkchlhtilrlptgiFyaqgVkTnvlfftkgtvanpnqdknctddvwvydlrtnmpsfgkrtpftdehlqpfervygedphglsprtegewsfnaeetevadseenkntdqhlatsrwrkfsrewirtaksdsldiswlkdkdsidadslpepdvlaaeamgelvqalseldalmrelgasdeadlqrqlleeafggvke
interface signature	TYSSFNNERRYNDKQK/QNFFV/QNFFVT

Estimated binding specificities ?

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# IC=14.667 IC/col=0.772 n_of_columns=19

specificity:

A |   9   0  24   9  96  96   0  24  24  24  24  24   9   0   0   0   0  96  96
C |  11   0  24  67   0   0  96  24  24  24  24  24  69   0   0   0  96   0   0
G |  67   0  24   9   0   0   0  24  24  24  24  24   9  96   0  96   0   0   0
T |   9  96  24  11   0   0   0  24  24  24  24  24   9   0  96   0   0   0   0

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updated Wed Jun 24 13:58:12 2026