3cbb_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HEPATOCYTE NUCLEAR FACTOR 4ALPHA IN COMPLEX WITH DNA: DIABETES GENE PRODUCT
reference	Melikishvili et al.
source	Homo sapiens
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3cbb_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3cbb_A interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqne > 3cbb_B interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqnerd
interface signature	DKRR/DKRR

Estimated binding specificities ?

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# IC=10.670 IC/col=0.889 n_of_columns=12

specificity:

A |   5   0  76  87   0  14  24   4   0   0  70   0
C |   4   0   8   1  96  62  24   5   0   0   4  96
G |   8  96   4   4   0   8  24   4  96  96  12   0
T |  79   0   8   4   0  12  24  83   0   0  10   0

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updated Tue Jul 29 20:08:32 2025