3cbb_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HEPATOCYTE NUCLEAR FACTOR 4ALPHA IN COMPLEX WITH DNA: DIABETES GENE PRODUCT
reference	Melikishvili et al.
source	Homo sapiens
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3cbb_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3cbb_A interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqne > 3cbb_B interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqnerd
interface signature	DKRR/DKRR

Estimated binding specificities ?

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# IC=11.028 IC/col=0.919 n_of_columns=12

specificity:

A |   0   4   0   0  91  24  24   0   0   9   0  76
C |   0  16  96  96   4  24   4   0   5  16  96   4
G |  96   4   0   0   0  24  59  96   0   4   0  12
T |   0  72   0   0   1  24   9   0  91  67   0   4

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updated Wed Jun 24 15:20:40 2026