interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A P53 CORE TETRAMER BOUND TO DNA
(mouse p53 core domain)
referenceOncogene 28 325 2009
sourceMus musculus
experimentX-ray (resolution=2.00, R-factor=?)
structural superfamilyp53-like transcription factors;
sequence familyP53 DNAbinding domain;
multimeric complexes2geq_AB 3exj_AB
redundant complexes2geq_B 3exl_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRACR

Estimated binding specificities ?

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# IC=3.181 IC/col=0.636 n_of_columns=5 specificity:   
A |  29  24   0   0  13
C |  54  24   0   0  41
G |   0  24   0  96  27
T |  13  24  96   0  15
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: P53
AGACATGCCTAGACATGCCTPubMed3exj_AB(7.71e-04)

Dendrogram of similar interfaces ?

matrix format
  
  --------ATCTRG                                       +3qyn_C    
                         +-----------------------------1 
  ------------RG       +-2                             +7b4n_A    
                       ! ! 
  RGRT----VCDCRG   L --3 +-----------------------------3wu1_A    
                       ! 
  RG--TCSC------       +-----------------------------2x6v_A    
                     

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updated Sun Aug 3 06:49:21 2025