3kqu_DEF : 3D-footprint complex

structure name	THREE CONFORMATIONAL SNAPSHOTS OF THE HEPATITIS C VIRUS NS3 HELICASE REVEAL A RATCHET TRANSLOCATION MECHANISM
reference	Rice et al. Proc.Natl.Acad.Sci.USA 107 521 2010
source	Hepatitis C virus
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
reference complex	3kqh_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kqu_D interface=108,205,224,244,246,260,305,368, sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgidpnirtgvrtittgapitystygkfladggcsggaydiiicdechstDsttilgigtvldqaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifchskkkcdelaaklsglglnavayyRgldvsviptsgdvivvatDalmtgftgdfdsvidcntcVtQtvdfsldptftieTttvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfdssvlcEcydagcawyeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahflsqtkqagdNfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqnevttthpitkyimacmsa > 3kqu_E interface=108,110,205,224,244,246,260,305,313,314,364,368, sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgidpnirtgvrtittgapitystygkfladggcsggaydiiicdechstDsTtilgigtvldqaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifchskkkcdelaaklsglglnavayyRgldvsviptsgdvivvatDalmtgftgdfdsvidcntcVtQtvdfsldptftieTttvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfdssvlcEcydagcaWYeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahflsqtkQagdNfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqnevttthpitkyimacmsa > 3kqu_F interface=108,110,205,224,244,246,260,305,313,314,364,368, sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgidpnirtgvrtittgapitystygkfladggcsggaydiiicdechstDsTtilgigtvldqaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifchskkkcdelaaklsglglnavayyRgldvsviptsgdvivvatDalmtgftgdfdsvidcntcVtQtvdfsldptftieTttvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfdssvlcEcydagcaWYeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahflsqtkQagdNfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqnevttthpitkyimacmsa
interface signature	DRDVQTEN/DTRDVQTEWYQN/DTRDVQTEWYQN

Estimated binding specificities ?

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# IC=18.515 IC/col=1.234 n_of_columns=15

specificity:

A |   0   0   0   0   0   7   0   0   0   0   0   7   0   0   0
C |   0   0   0   0   0   7   0   0   0   0   0   7   0   0   0
G |   0   0   0   0   0   7   0   0   0   0   0   8   0   0   0
T |  96  96  96  96  96  75  96  96  96  96  96  74  96  96  96

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updated Mon Sep 9 18:29:07 2024