3kqh_B : 3D-footprint complex

structure name	THREE CONFORMATIONAL SNAPSHOTS OF THE HEPATITIS C VIRUS NS3 HELICASE REVEAL A RATCHET TRANSLOCATION MECHANISM (Serine proteaseNTPasehelicase NS3)
reference	Rice et al. Proc.Natl.Acad.Sci.USA 107 521 2010
source	Hepatitis C virus
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;
multimeric complexes	3kqu_ABC 3kqu_DEF
redundant complexes	3kqk_A 3kql_B 3kqu_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kqh_B interface=110,181,205,244,246,260,261,262,305,313,314,368, sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgidpnirtgvrtittgapitystygkfladggcsggaydiiicdechstdsTtilgigtvldqaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifcHskkkcdelaaklsglglnavayyRgldvsviptsgdvivvatdalmtgftgdfdsvidcntcVtQtvdfsldptftieTTTvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfdssvlcEcydagcaWYeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahflsqtkqagdNfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqnevttthpitkyimacms
interface signature	THRVQTTTEWYN

Estimated binding specificities ?

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# IC=6.676 IC/col=1.113 n_of_columns=6

specificity:

A |  96  96  96  96  31  96
C |   0   0   0   0  21   0
G |   0   0   0   0  21   0
T |   0   0   0   0  23   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------TAHARA----VAQATATATA--EAWAYANA   L            +-----------------3kqh_B    
                                               +------1 
  DCHA----------NT--------------------       +-2      +-----------------6znp_A    
                                             ! ! 
  ----RA--------------------KC--------     --3 +------------------------7aud_E    
                                             ! 
  ------------TG----------------------       +--------------------------7vdt_A

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updated Sun Aug 3 07:09:44 2025