3mis_AB : 3D-footprint complex

structure name	I-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-8G)
reference	Stoddard et al. 'Nucleic 38 5601 2010
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Homing endonucleases;
reference complex	2fld_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3mis_A interface=19,21,23,25,27,29,30,36,38,44,67,70,72,74,80, tlqpteaayiagfldgdgSiYaKlEpRpDYkdikyQvRlaisfIqrkdkfpylqdiydqlgkrgnlRkdRgDgIadytiYgsthlsiilpdlvpylrikkkqanrilhiinlypqaqknpskfldlvkivddvqnlnkradelkstnydrlleeflkagki > 3mis_B interface=19,21,23,25,27,29,30,36,38,44,67,70,72,74,80, tlqpteaayiagfldgdgSiYaKlEpRpDYkdikyQvRlaisfIqrkdkfpylqdiydqlgkrgnlRkdRgDgIadytiYgsthlsiilpdlvpylrikkkqanrilhiinlypqaqknpskfldlvkivddvqnlnkradelkstnydrlleeflkagki
interface signature	SYKERDYQRIRRDIY/SYKERDYQRIRRDIY

Estimated binding specificities ?

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# IC=28.102 IC/col=1.171 n_of_columns=24

specificity:

A |  21   0   0  96   0   0   0   0   0   0   0  21  24   0   0  96   0   0   0   0   0   0   0   0
C |  33   0   0   0   0  96   0   0   0  96   0  42  24  96   0   0  96   0   0  96  96   0   0  96
G |  21  96  96   0  96   0   0  96   0   0   0  12  24   0  96   0   0  96   0   0   0   0  96   0
T |  21   0   0   0   0   0  96   0  96   0  96  21  24   0   0   0   0   0  96   0   0  96   0   0

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updated Mon Jan 5 05:40:29 2026