3mis_AB : 3D-footprint complex

structure name	I-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-8G)
reference	Stoddard et al. 'Nucleic 38 5601 2010
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Homing endonucleases;
reference complex	2fld_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3mis_A interface=19,21,23,25,27,29,30,36,38,44,67,70,72,74,80, tlqpteaayiagfldgdgSiYaKlEpRpDYkdikyQvRlaisfIqrkdkfpylqdiydqlgkrgnlRkdRgDgIadytiYgsthlsiilpdlvpylrikkkqanrilhiinlypqaqknpskfldlvkivddvqnlnkradelkstnydrlleeflkagki > 3mis_B interface=19,21,23,25,27,29,30,36,38,44,67,70,72,74,80, tlqpteaayiagfldgdgSiYaKlEpRpDYkdikyQvRlaisfIqrkdkfpylqdiydqlgkrgnlRkdRgDgIadytiYgsthlsiilpdlvpylrikkkqanrilhiinlypqaqknpskfldlvkivddvqnlnkradelkstnydrlleeflkagki
interface signature	SYKERDYQRIRRDIY/SYKERDYQRIRRDIY

Estimated binding specificities ?

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# IC=18.994 IC/col=0.791 n_of_columns=24

specificity:

A |  19  14   0  96   0   9   0   0   0   6  13  21  24  13  13  85   6   0   0   3   0   0   6  15
C |  39  16   0   0   0  67   0   0   0  78  10  33  24  56  10   3  78   0   0  85  96   0   6  51
G |  19  52  96   0  96   9   0  96   0   6  10  21  24  14  63   3   6  96   0   5   0   0  78  15
T |  19  14   0   0   0  11  96   0  96   6  63  21  24  13  10   5   6   0  96   3   0  96   6  15

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updated Tue Jul 29 22:06:27 2025