interface graph thumbnail
legend  pdf

structure nameEARLY B-CELL FACTOR 1 (EBF1) BOUND TO DNA
(Transcription factor COE1)
referenceGrosschedl et al. 'Genes 24 2270 2010
sourceMus musculus
experimentX-ray (resolution=2.80, R-factor=0.207)
structural superfamilyE set domains;
sequence familyIPT/TIG domain;
multimeric complexes3mlp_EF
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNRNANNNSK

Estimated binding specificities ?

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# IC=6.672 IC/col=0.667 n_of_columns=10 specificity:   
A |  11  24  24  24   0   0   0   0  69  67
C |  67  24  24  24   0   0   0   0   9  11
G |   9  24  24  24   0  96  96  96   9   9
T |   9  24  24  24  96   0   0   0   9   9
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGSTNTRCNCATNTNCNTSGKG--------   L                     +--------3mlp_F    
                                       +-----------------1 
  RGSTNTRCNGATNANCNTSGKG--------   L   !                 +--------3mln_A    
                                     --4 
  ------------------------KT----   L   !         +----------------2ram_A    
                                       +---------3 
  ----------------------QA------   L             !   +------------1imh_C    
                                                 +---2 
  --------------------------KARC   L                 +------------1p7h_L    
                                     

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updated Fri Sep 13 17:26:12 2024