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structure nameMOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
referenceSubramanian et al. 'Nucleic 39 729 2011
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.30, R-factor=?)
structural superfamilyHoming endonucleases;
reference complex1t9i_B 3mxb_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQNNSRRYTYRVQKT/SIQKRSNQSATYSVDRSKT

Estimated binding specificities ?

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# IC=23.342 IC/col=1.015 n_of_columns=23 specificity:   
A |   0  24   0   0   0   2   0   0  96   5   5   2   7   7   2  12   0  96   0  24  82   0  96
C |   0  24   0   0   0  88   0   0   0   9   5   4   4  70  82   0   0   0   0  24   7  96   0
G |   0  24   0  96  96   2   0  96   0  80  78   2   2   7   5   0  96   0  96  24   5   0   0
T |  96  24  96   0   0   4  96   0   0   2   8  88  83  12   7  84   0   0   0  24   2   0   0
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updated Mon Sep 9 19:14:57 2024