6fb0_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TAILORED I-CREI HOMING ENDONUCLEASE PROTEIN (3115 VARIANT) IN COMPLEX WITH ITS TARGET DNA (HAEMOGLOBIN BETA SUBUNIT GENE) IN THE PRESENCE OF CALCIUM (DNA ENDONUCLEASE I-CREI)
reference	Molina et al. 'Sci 8 10286 2018
source	CHLAMYDOMONAS REINHARDTII
experiment	X-ray (resolution=2.15, R-factor=0.180)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
multimeric complexes	2xe0_AB 3mxb_AB 3mxb_RS 6fb0_AB 6fb5_AB
redundant complexes	3mx9_A 3mxb_B 2xe0 6fb5
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fb0_A interface=21,23,25,27,29,31,37,39,43,45,65,67,69,72,74,76,138,139, ntkynkefllylagfvdsdgSiIaQiKpNqSvkfkhRlQltfDvTqktqrrwfldklvdeigvgYvAdSgsVsKyRlseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqiaalndsKTrkttsetvravlds
interface signature	SIQKNSRQDTYASVKRKT

Estimated binding specificities ?

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# IC=8.745 IC/col=0.972 n_of_columns=9

specificity:

A |   6  78   0   0  78   0  78   0  78
C |   6   6   0   0   6   0   6  96   6
G |   6   6  96  96   6  96   6   0   6
T |  78   6   0   0   6   0   6   0   6

scan!

Dendrogram of similar interfaces ?

matrix format

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updated Mon Jun 29 22:52:34 2026