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structure nameCRYSTAL STRUCTURE OF A TAILORED I-CREI HOMING ENDONUCLEASE PROTEIN (3115 VARIANT) IN COMPLEX WITH ITS TARGET DNA (HAEMOGLOBIN BETA SUBUNIT GENE) IN THE PRESENCE OF CALCIUM
(DNA ENDONUCLEASE I-CREI)
referenceMolina et al. 'Sci 8 10286 2018
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.15, R-factor=0.180)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes6fb0_AB 6fb5_AB
redundant complexes6fb5
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKNSRQDTYASVKRKT

Estimated binding specificities ?

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# IC=8.745 IC/col=0.972 n_of_columns=9 specificity:   
A |   6  78   0   0  78   0  78   0  78
C |   6   6   0   0   6   0   6  96   6
G |   6   6  96  96   6  96   6   0   6
T |  78   6   0   0   6   0   6   0   6
scan!

Dendrogram of similar interfaces ?

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updated Fri Sep 13 21:38:21 2024