interface graph thumbnail
legend  pdf

structure nameRNA POLYMERASE ALPHA C-TERMINAL DOMAIN (E. COLI) AND SIGMA REGION 4 (T. AQ. MUTANT) BOUND TO (UP,-35 ELEMENT) DNA
referenceLara-Gonzalez et al. Biochemistry 59 4523 2020
sourceESCHERICHIA COLI / THERMUS AQUATICUS
experimentX-ray (resolution=3.25, R-factor=?)
structural superfamilySigma3 and sigma4 domains of RNA polymerase sigma factors;
reference complex3n97_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLETRERRQ/R/R

Estimated binding specificities ?

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# IC=5.005 IC/col=1.001 n_of_columns=5 specificity:   
A |   0   0  78  85   4
C |   0  96   6   5   4
G |   0   0   6   3  81
T |  96   0   6   3   7
scan!

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updated Tue Jul 29 22:13:41 2025