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structure nameCRYSTAL STRUCTURE OF A DIMER OF NOTCH TRANSCRIPTION COMPLEX TRIMERS ON HES1 DNA
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceBlacklow et al. Nat.Struct.Mol.Biol. 17 1312 2010
sourceHOMO SAPIENS
experimentX-ray (resolution=3.45, R-factor=0.256)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKKSQ

Estimated binding specificities ?

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# IC=5.055 IC/col=0.632 n_of_columns=8 specificity:   
A |   7  24   7   9  24   0  96  66
C |  75  24   7   7  24   0   0   9
G |   7  24   1  73  24  96   0  14
T |   7  24  81   7  24   0   0   7
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updated Thu Sep 12 17:45:18 2024