interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PFV S217Q MUTANT INTASOME IN COMPLEX WITH MANGANESE
(PFV integrase)
referenceCherepanov et al. Proc.Natl.Acad.Sci.USA 107 20057 2010
sourceHuman spumaretrovirus
experimentX-ray (resolution=2.72, R-factor=0.212)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
reference complex3oym_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERP

Estimated binding specificities ?

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# IC=1.998 IC/col=0.500 n_of_columns=4 specificity:   
A |  16   9  67   2
C |  16  11   9  88
G |  16  67  11   4
T |  48   9   9   2
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updated Thu Jan 8 22:32:09 2026