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structure nameCRYSTAL STRUCTURE OF THE PFV N224H MUTANT INTASOME BOUND TO MANGANESE
(PFV INTEGRASE)
referenceCherepanov et al. Proc.Natl.Acad.Sci.USA 107 20057 2010
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.02, R-factor=0.199)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
redundant complexes3l2q_A 3l2r_A 3l2u_A 3l2v_A 3l2w_A 3oy9_A 3oya_A 3oyb_A 3oyc_A 3oyd_A 3oye_A 3oyf_A 3oyg_A 3oyh_A 3oyi_A 3oyj_A 3oyk_A 3oyl_A 3oyn_A 3s3m_A 3s3n_A 3s3o_A 4bac_A 4bdy_A 4bdz_A 4be0_A 4be1_A 4be2_A 4e7h_A 4e7i_A 4ikf_A 4ztf_A 4ztj_A 5frm_A 5frn_A 5fro_A 5mma_A 5mmb_A 5no1_A 5uop_A 5uoq_A 7adu_A 7adv_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERP

Estimated binding specificities ?

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# IC=2.308 IC/col=0.577 n_of_columns=4 specificity:   
A |  16   9  74   1
C |  16   9   7  92
G |  19  69   8   1
T |  45   9   7   2
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ITLTRTPTKT--HTETPAQA--EARC------PTKALTNTVATA   L           +---------------3oym_A    
                                                     +-------2 
  ------------------QG--ECSG--HCQT------------       !       +---------------6rwm_A    
                                                   --4 
  ------------------QG--ECSCKG----------------       !                    +--6vdk_A    
                                                     !  +-----------------1 
  ------------QT--PAQGAGECRGQG----------------   L   +--3                 +--7u32_A    
                                                        ! 
  ------NT--WA--TA--QGAGECRTRC----------------   L      +--------------------7jn3_E    
                                                   

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updated Fri Sep 13 17:32:55 2024