interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PFV S217Q MUTANT INTASOME IN COMPLEX WITH MAGNESIUM AND THE INSTI MK2048
(PFV INTEGRASE)
referenceCherepanov et al. Proc.Natl.Acad.Sci.USA 107 20057 2010
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.68, R-factor=0.207)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
reference complex3oym_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERSP

Estimated binding specificities ?

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# IC=2.242 IC/col=0.560 n_of_columns=4 specificity:   
A |  16   8  70   1
C |  16   8   8  92
G |  19  70   8   1
T |  45  10  10   2
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updated Thu Sep 12 17:52:11 2024