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structure nameASYMMETRIC ASSEMBLY OF MERKEL CELL POLYOMAVIRUS LARGE T-ANTIGEN ORIGIN BINDING DOMAINS AT THE VIRAL ORIGIN
referenceHarrison et al. J.Mol.Biol. 409 529 2011
sourceMerkel cell polyomavirus
experimentX-ray (resolution=2.90, R-factor=?)
structural superfamilyOrigin of replication-binding domain, RBD-like;
reference complex3qfq_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSNKTR/SNKTR/SNKTR

Estimated binding specificities ?

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# IC=18.587 IC/col=0.845 n_of_columns=22 specificity:   
A |   0  24   0   7   0   0  24  24  24  96   0   0   9   4   0  24  96   0  10  14   6  72
C |   0  24   0  76  96   0  24  24  24   0   0  96  86  81  96  24   0   0  86  76   4   9
G |  96  24  96   9   0   0  24  24  24   0  96   0   1   7   0  24   0  96   0   0  14   4
T |   0  24   0   4   0  96  24  24  24   0   0   0   0   4   0  24   0   0   0   6  72  11
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updated Wed Jun 24 17:49:03 2026