interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS (PFV) INTASOME IN COMPLEX WITH MAGNESIUM AND DOLUTEGRAVIR (S/GSK1349572)
(PFV INTEGRASE)
referenceCherepanov et al. Mol.Pharmacol. 80 565 2011
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.49, R-factor=0.207)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
reference complex3oym_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERSP

Estimated binding specificities ?

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# IC=2.148 IC/col=0.537 n_of_columns=4 specificity:   
A |   6   7   7  45
C |   6   4  74  19
G |  78   4   7  16
T |   6  81   8  16
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updated Thu Sep 12 18:12:06 2024