3si6_A : 3D-footprint complex

structure name	RB69 DNA POLYMERASE TRIPLE MUTANT (L561A/S565G/Y567A) TERNARY COMPLEX WITH DUPNPP AND A DEOXY-TERMINATED PRIMER IN THE PRESENCE OF MG2+ (DNA polymerase)
reference	Konigsberg et al. Biochemistry 50 9114 2011
source	Enterobacteria phage RB69
experiment	X-ray (resolution=1.85, R-factor=0.185)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
sequence family	DNA polymerase family B, exonuclease do;
reference complex	3qex_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3si6_A interface=622,706,734,800, mkefyltveqigdsiferyidsngrertreveykpslfahcpesqatkyfdiygkpctrklfanmrdasqwikrmediglealgmddfklaylsdtynyeikydhtkirvanfdievtspdgfpepsqakhpidaithydsiddrfyvfdllnspygnveewsieiaaklqeqggdevpseiidkiiympfdnekellmeylnfwqqktpviltgwnvesfaipyvynriknifgestakrlsphrktrvkvienmygsreiitlfgisvldyidlykkfsftnqpsysldyisefelnvgklkydgpisklresnhqryisyniiavyrvlqidakrqfinlsldmgyyakiqiqsvfspiktwdaiifnslkeqnkvipqgrshpvqpypgafvkepipnrykyvmsfdltslypsiirqvnispetiagtfkvaplhdyinavaerpsdvyscspngmmyykdrdgvvpteitkvfnqrkehkgymlaaqrngeiikealhnpnlsvdepldvdyrfdfsdeikekikklsakslnemlfraqrtevagmtaqinrkalinglagalgnvwfryydlrnataittfgqmalqwierkvneylnevcgtegeafvlygdTdsiyvsadkiidkvgeskfrdtnhwvdfldkfarermepaidrgfremceymnnkqhlmfmdreaiagpplgskgiggfwtgkKryalnvwdmegtryaepklkimgletqKsstpkavqkalkecirrmlqegeeslqeyfkefekefrqlnyisiasvssanniakydvggfpgpKcpfhirgiltynraikgnidapqvvegekvyvlplregnpfgdkciawpsgteitdlikddvlhwmdytvllektfikplegftsaakldyekkaslfdmfaf
interface signature	TKKK

Estimated binding specificities ?

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# IC=2.635 IC/col=0.329 n_of_columns=8

specificity:

A |  53   1  24  24  24  24   7  73
C |   7  88  24  24  24  24   7   9
G |  14   0  24  24  24  24   1   7
T |  22   7  24  24  24  24  81   7

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updated Thu Sep 12 18:13:57 2024