interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF HUMAN NOTCH1 TRANSCRIPTION COMPLEX INCLUDING CSL, RAM, ANK, AND MAML-1 ON HES-1 PROMOTER DNA SEQUENCE
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceBlacklow et al. Structure 20 340 2012
sourceHOMO SAPIENS
experimentX-ray (resolution=3.85, R-factor=0.213)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKSQ

Estimated binding specificities ?

contactlogo
# IC=7.073 IC/col=0.884 n_of_columns=8 specificity:   
A |   4   0   4   6   6  84   4  82
C |   4   0  84  82  82   4  82   4
G |   4   0   4   4   4   4   6   6
T |  84  96   4   4   4   4   4   4
scan!

home
updated Thu Sep 12 18:30:12 2024