3wtu_AC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1 (V170A), RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
reference	Shiina et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	p53-like transcription factors;"Winged helix" DNA-binding domain;
reference complex	3wts_A 4l18_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wtu_A interface=21,83,111,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvakgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitADgpRepR > 3wtu_C interface=70,73,76,77, pvipaaalagytgsgpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvk
interface signature	RRADRR/KRRY

Estimated binding specificities ?

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# IC=10.314 IC/col=1.031 n_of_columns=10

specificity:

A |  78   0   0  89   6   0   6   0   0   6
C |   6   0   0   6   9   0   6   0   0  75
G |   6  96  96   1   6  96   6  96  96   6
T |   6   0   0   0  75   0  78   0   0   9

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updated Wed Jul 30 00:05:45 2025